LC/MS Analysis of 1,3-Dimethylamylamine (DMAA) in Natural and Spiked Geranium Oil on AZYP LARIHC™ CF6-P

LC/MS Analysis of 1,3-Dimethylamylamine (DMAA) in Natural and Spiked Geranium Oil on AZYP LARIHC™ CF6-P

Conditions

column AZYP LARIHC CF6-P, 15 cm x 2.1 mm I.D., 5 µm particles (Available from Supelco, Please inquire)
mobile phase [A] acetonitrile; [B] methanol; [C] formic acid; (90:10:0.1, A:B:C)
flow rate 0.1 mL/min
sample Geranium oil, natural and spiked with 100 ppb synthetic DMAA
detector MS, ESI-LIT(+), SIM, m/z 116.2

Description

Analysis Note 1,3-Dimethylamylamine (DMAA) is a stimulant found in various health supplements. Although often labelled as "natural," derived from geranium plants, it is suspected of actually having synthetic origins. If synthetic, then the supplement would fall under FDA regulations. This study showed that natural geranium oil does not contain detectable levels of DMAA. A modified cyclofructan HPLC columns, LARIHC CF6-P, was used for the analysis.
Categories Analytical Chromatography, Stimulants
Featured Industry Vitamins, Nutraceuticals, and Natural Products
Legal Information LARIHC is a trademark of AZYP, LLC
suitability application for LC-MS

Materials

     
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