LC/MS Analysis of Sertraline and Norsertraline on Ascentis® Express RP-Amide

LC/MS Analysis of Sertraline and Norsertraline on Ascentis® Express RP-Amide

Conditions

column Ascentis Express RP Amide, 10 cm x 3.0 mm I.D., 2.7 µm particles (53918-U)
column temp. 55 C
mobile phase [A] 10 mM ammonium formate, water, pH 3.6; [B] 10 mM ammonium formate, acetonitrile, pH 3.6; (65:35, A:B)
flow rate 0.6 ml/min
sample 200 ng/mL in 25:75, water: acetonitrile
injection 2 µl
detector ESI(+), 100-1000 m/z

Description

Categories Analytical Chromatography, Clinical, antidepressants, Antidepressants
Featured Industry Clinical
Pharmaceutical (small molecule)
Legal Information Ascentis is a registered trademark of Sigma-Aldrich Co. LLC
suitability application for HPLC

Materials

     
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