Hormone Standards

Over the past 17 years, hormone testing has increased significantly in the clinical laboratory setting as advances in the specificity and selectivity of LC-MS/MS technology have enabled hormones to serve as biomarkers for a variety of diseases from congenital disorders, heart disease, and psychiatric illnesses to numerous cancers.1,2 Newborn screening of hormones, for example, is routinely performed to aid in the diagnosis of congenital adrenal hyperplasia (CAH).3

In addition to their use in established screening applications, hormones have shown efficacy in the treatment and diagnosis of severe pain. In recent years, pain management clinics have been incorporating hormone testing protocols to determine a patient’s degree of pain and whether patient hormone replacement therapy is required.4

Sigma-Aldrich's Cerilliant brand provides innovative solution-based reference standards for use in a variety of analytical applications ranging from clinical and diagnostic testing, toxicology, and therapeutic drug monitoring to emerging applications in endocrinology, clinical chemistry and pain management. Cerilliant’s comprehensive listing includes parent drug, metabolite, and internal standard Certified Spiking Solutions® of neonatal, male and female, and thyroid hormones as well as catecholamines and 25-Hydroxyvitamin D. Our Certified Spiking Solutions® are manufactured and certified to the highest industry standards including ISO Guide 34, ISO/IEC 17025, and ISO 13485, and are compliant with ISO 17511 and ISO 15194.

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