Attention:

Certain features of Sigma-Aldrich.com will be down for maintenance the evening of Friday August 18th starting at 8:00 pm CDT until Saturday August 19th at 12:01 pm CDT.   Please note that you still have telephone and email access to our local offices. We apologize for any inconvenience.

Laminin

By: George Sitterley, BioFiles 2008, 3.8, 11.

BioFiles 2008, 3.8, 11.

Laminin has active domains for collagen binding, cell adhesion, heparin binding, and neurite outgrowth (PHD) fragment.1 Laminin chains are designated A (molecular weight 400kDa), B1 (molecular weight 210 kDa) and B2 (molecular weight 200 kDa). The cohesion between these chains is the result of many inter- and intrachain disulfide bonds. Together, they cause the molecule to look like a crucifix.

Laminin is a ubiquitous non-collagenous connective tissue glycoprotein that is a major constituent of basement membranes.


Laminins

Name Source Storage Temp Target Cells For Attachment Concentration For Use Cat. No.
Laminin, aqueous solution from Engelbreth- Holm-Swarm murine sarcoma basement membrane

−20°C

Epithelial cells, endothelial cells, muscle cells, tumor cells, hepatocytes, Schwannoma

1 ‑ 2 μg/cm2

L2020-1MG
Laminin, liquid from human placenta

−70°C

Epithelial cells, endothelial cells, muscle cells, tumor cells, hepatocytes, Schwannoma

1 ‑ 2 μg/cm2

L6274-.5MG

back to top Back to Top

Materials

References

  1. Kleinman, H. K., et al., Use of extracellular matrixcomponents for cell culture. Anal. Biochem., 166, 1-13 (1987).

back to top Back to Top

Related Links

Categories