New Aromatic Terminal Alkynes

The terminal alkyne functionality has a wide range of applications including most recently the synthesis of spiropyran substituted 2,3-dicyanopyrazines¹ and (±)-asteriscanolide,² as well as conversion to enamines using resin-bound 2° amines.³ Sigma-Aldrich offers a number of aromatic alkynes that can further enhance the reactivity of the alkyne group resulting in many new reactions and products for organic synthesis and medicinal chemistry.

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Materials

1. Lee, B. et al. Bull. Korean Chem. Soc. 2002, 23(8), 1.
2. Drafft, M. E. et al. Synthesis 2000, 1020.
3. Aznar, F. et al. Tetrahedron Lett. 2000, 41, 5683.

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