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Iodinated Building Blocks

By: Mark Redlich, Chemfiles Volume 10 Article 3

Iodine-containing substrates are valuable building blocks for a diverse array of synthetic methodologies. They have the ability to participate in various cross-coupling reactions for the generation of carbon–carbon, carbon–nitrogen, and carbon– oxygen bonds. Often iodinated substrates are preferred to the brominated analogs, due to cleaner reactions. They are also handy precursors for the formation of organolithium, organozinc, or organomagnesium reagents. Sigma-Aldrich is pleased to offer these useful building blocks for your research.

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