Anita Mattson - Professor Product Portal

Professor Product Portal Index

 

Professor Anita Mattson

Boronate ureas benefit from internal Lewis acid coordination of the urea cabonyl oxygen and the strategically placed boron. As a result of this structural feature, boronate ureas can be rendered more acidic than conventional urea hydrogen bond donor catalysts. These more acidic boronate ureas are stable, storable, easy to use, and can enable enhanced and/or unique reactivity patterns when compared to conventional urea catalysts.

Mattson Group Website
Link to Aldrichimica Acta review (2016)

For recent articles from the Mattson Laboratory:

Materials

     
Sonia S So, Anita E Mattson
Journal of the American Chemical Society 2012-05-30
The combination of a urea catalyst and an α-nitro-α-diazo ester gives rise to a reactive species able to undergo insertion into the N-H bonds of anilines. This new strategy to achieve N-H insertion reactivity is in contrast to typical metal-catalyzed conditions for the generation of carbenoids from α-diazocarbonyl compounds. Thi...Read More
Tyler J Auvil, Sonia S So, Anita E Mattson
Angewandte Chemie. International edition in English 2013-10-18
It takes two: A unique organocatalyzed cascade for the unsymmetric double arylation of α-nitrodiazoesters is described. This organocascade features the strategic use of carbene-activating anilines in conjunction with a urea catalyst, thus allowing for the synthesis of pharmaceutically attractive α-diarylesters through a transien...Read More
Erica D Couch, Tyler J Auvil, Anita E Mattson
Chemistry: A European Journal 2014-07-01
The enhanced catalytic activity of difluoroboronate ureas proved to be essential as an acidity amplifier to promote metal-free O-H and S-H insertion reactions of α-aryldiazoacetates in high yield. This methodology was found to be generally applicable to a broad substrate scope and presents a conceptually new approach for organoc...Read More
Related Links