HomeWebinarsCalcium Carbonate as TiO2 Alternative in Coating: The Importance of Particle Engineering

Calcium Carbonate as TiO2 Alternative in Coating: The Importance of Particle Engineering


Uniform colored and white coatings applied to tablets create a homogeneous appearance, improving patient compliance. Concerns about titanium dioxide have led to an increased interest in suitable alternatives. Calcium carbonate is currently seen as the most likely alternative.

This webinar highlights how particle engineering supports the optimal performance of calcium carbonate in coating applications, comparing our new alternative to titanium dioxide, the industry benchmark. We will present comprehensive study results of color measurements and provide you with tools on how to optimize coating formulation development and achieve appealing white finishings without titanium dioxide.

In this webinar, you will learn:

  • The latest regulatory trends and implications in the EU for titanium dioxide, the extensively used colorant and opacifier in medicinal products
  • How particle engineering supports optimal performance of calcium carbonate in film coatings, comparing the product to titanium dioxide
  • How high efficiency can be maintained in the spraying process
  • How color measurements and screening methods can be utilized to optimize the final finishing in the formulation development


Almut von der Brelie

Almut von der Brelie


Senior Manager Strategic Marketing, Excipients for Solid Applications

Almut von der Brelie has more than 15 years of experience in the industry for functional cosmetic, food, and pharmaceutical ingredients used in highly regulated markets. In her current position as a strategic marketing manager, she is responsible for a sweetener portfolio and product innovations focusing on oral solid dosage form applications. She led several projects for sensory studies on food additives and consumer acceptance. Almut studied food chemistry at the Technical University Braunschweig, Germany.

Thomas Kipping, Ph.D.

Thomas Kipping, Ph.D.


Head of Drug Carriers

Dr. Thomas Kipping is an expert in the field of pharmaceutical technology and formulation development. Thomas is currently the head of drug carriers at Merck. With more than 10 years of industrial experience, spanning various sectors within the pharmaceutical industry, including drug product development and CDMO services, he has consistently demonstrated a strong commitment to advancing pharmaceutical sciences and enhancing drug development processes He holds a Ph.D. in pharmaceutical technology from the University of Bonn.

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