CFH
complement factor H
Synonyms:
AHUS1, AMBP1, ARMD4, ARMS1, CFHL3, FH, FHL1, HF, HF1, HF2, HUS
Species:
Human CFH (3075), Mouse Cfh (12628), Rat Cfh (155012), chicken CFH (429057), Zebrafish cfh (553297), dog CFH (478952), Domestic Rabbit CFH (100340175), sheep CFH (100174982), cow CFH (280816), Horse CFH (100051358) ...More
UniProtKB ID:
Gene ID:
- Human(3075) Summary: This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Oct 2011]
- Mouse(12628) complement component factor h
- Rat(155012) complement factor H
- chicken(429057) complement factor H
- Zebrafish(553297) complement factor H
- dog(478952) complement factor H
- Domestic Rabbit(100340175) complement factor H
- sheep(100174982) complement factor H
- cow(280816) complement factor H
- Horse(100051358) complement factor H
- naked mole-rat(101715308) complement factor H
- domestic guinea pig(100733902) complement factor H
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Complement factor H Antibody, clone 10M8Q5, Rabbit Monoclonal, ,
Species Reactivity
human
Application
western blot