ERLIN2
ER lipid raft associated 2
Synonyms:
C8orf2, Erlin-2, NET32, SPFH2, SPG18
Species:
Human ERLIN2 (11160), Mouse Erlin2 (244373), Rat Erlin2 (290823), chicken ERLIN2 (426769), dog ERLIN2 (607518), cow ERLIN2 (616278), Domestic Rabbit ERLIN2 (100354383), domestic cat ERLIN2 (101089349), naked mole-rat Erlin2 (101714906), sheep ERLIN2 (101110479) ...More
UniProtKB ID:
Gene ID:
- Human(11160) Summary: This gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1,4,5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia-18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
- Mouse(244373) ER lipid raft associated 2
- Rat(290823) ER lipid raft associated 2
- chicken(426769) ER lipid raft associated 2
- dog(607518) ER lipid raft associated 2
- cow(616278) ER lipid raft associated 2
- Domestic Rabbit(100354383) ER lipid raft associated 2
- domestic cat(101089349) ER lipid raft associated 2
- naked mole-rat(101714906) ER lipid raft associated 2
- sheep(101110479) ER lipid raft associated 2
- Zebrafish(100151163) ER lipid raft associated 2
- domestic guinea pig(100734771) ER lipid raft associated 2
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