F5
coagulation factor V (proaccelerin, labile factor)
Synonyms:
FVL, PCCF, RPRGL1, THPH2
Species:
Human F5 (2153), Mouse F5 (14067), Rat F5 (304929), naked mole-rat F5 (101703568), domestic guinea pig F5 (100715882), sheep F5 (101123649), cow F5 (280687), Horse F5 (100058503), domestic cat F5 (101085264), dog F5 (100685858) ...More
UniProtKB ID:
Gene ID:
- Human(2153) Summary: This gene encodes an essential cofactor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The activated protein is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in this gene result in either an autosomal recessive hemorrhagic diathesis or an autosomal dominant form of thrombophilia, which is known as activated protein C resistance. [provided by RefSeq, Oct 2008]
- Mouse(14067) coagulation factor V
- Rat(304929) coagulation factor V (proaccelerin, labile factor)
- naked mole-rat(101703568) coagulation factor V (proaccelerin, labile factor)
- domestic guinea pig(100715882) coagulation factor V (proaccelerin, labile factor)
- sheep(101123649) coagulation factor V (proaccelerin, labile factor)
- cow(280687) coagulation factor V (proaccelerin, labile factor)
- Horse(100058503) coagulation factor V (proaccelerin, labile factor)
- domestic cat(101085264) coagulation factor V (proaccelerin, labile factor)
- dog(100685858) coagulation factor V (proaccelerin, labile factor)
- chicken(374052) coagulation factor V (proaccelerin, labile factor)
- Zebrafish(327320) coagulation factor V
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