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Merck

FGA

fibrinogen alpha chain

Synonyms:
Fib2
Species:
UniProtKB ID:
Gene ID:
  • Human(2243) Summary: The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus. [provided by RefSeq, Jul 2008]
  • Mouse(14161) fibrinogen alpha chain
  • Rat(361969) fibrinogen alpha chain
  • chicken(396307) fibrinogen alpha chain
  • Zebrafish(378986) fibrinogen alpha chain
  • cow(522039) fibrinogen alpha chain
  • Horse(100069763) fibrinogen alpha chain
  • domestic cat(101092934) fibrinogen alpha chain
  • dog(475473) fibrinogen alpha chain
  • naked mole-rat(101697611) fibrinogen alpha chain
  • domestic guinea pig(100720646) fibrinogen alpha chain
  • Domestic Rabbit(100353616) fibrinogen alpha chain
  • sheep(101102090) fibrinogen alpha chain

Custom & Knockdown Gene Products

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Fibrinogen alpha chain (FGA) antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-FGA Antibody, clone 4F6 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot

Proteins

Product Number
Description
Species
Fibrinopeptide A human, ≥96% (HPLC),
Species
human
Fibrinogen from human plasma, 50-70% protein (≥80% of protein is clottable),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human FGA (3),
Species
human
MISSION® esiRNA, targeting human FGA (4),
Species
human
MISSION® esiRNA, targeting human FGA (1),
Species
human
MISSION® esiRNA, targeting human FGA (2),
Species
human
MISSION® esiRNA, targeting mouse Fga,
Species
mouse