HPD
4-hydroxyphenylpyruvate dioxygenase
Synonyms:
4-HPPD, 4HPPD, GLOD3, HPPDASE, PPD
Species:
Human HPD (3242), Mouse Hpd (15445), Rat Hpd (29531), dog HPD (610778), chicken HPD (416852), cow HPD (516058), domestic cat HPD (101093465), Domestic Rabbit HPD (100347363), sheep HPD (101122814), naked mole-rat Hpd (101703926)
UniProtKB ID:
Gene ID:
- Human(3242) Summary: The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
- Mouse(15445) 4-hydroxyphenylpyruvic acid dioxygenase
- Rat(29531) 4-hydroxyphenylpyruvate dioxygenase
- dog(610778) 4-hydroxyphenylpyruvate dioxygenase
- chicken(416852) 4-hydroxyphenylpyruvate dioxygenase
- cow(516058) 4-hydroxyphenylpyruvate dioxygenase
- domestic cat(101093465) 4-hydroxyphenylpyruvate dioxygenase
- Domestic Rabbit(100347363) 4-hydroxyphenylpyruvate dioxygenase
- sheep(101122814) 4-hydroxyphenylpyruvate dioxygenase
- naked mole-rat(101703926) 4-hydroxyphenylpyruvate dioxygenase
- domestic guinea pig(100714633) 4-hydroxyphenylpyruvate dioxygenase
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