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Merck

ITGAM

integrin, alpha M (complement component 3 receptor 3 subunit)

Synonyms:
CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6
Species:
Human ITGAM (3684), Mouse Itgam (16409), Rat Itgam (25021), Horse ITGAM (100064803), dog ITGAM (489928), sheep ITGAM (443217), domestic guinea pig Itgam (100135561), domestic cat ITGAM (101087957), cow ITGAM (407124), naked mole-rat Itgam (101719288)
UniProtKB ID:
P11215, Q4VAK0, Q4VAK1, Q4VAK2
Gene ID:
  • Human(3684) Summary: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
  • Mouse(16409) integrin alpha M
  • Rat(25021) integrin, alpha M
  • Horse(100064803) integrin, alpha M (complement component 3 receptor 3 subunit)
  • dog(489928) integrin, alpha M (complement component 3 receptor 3 subunit)
  • sheep(443217) integrin, alpha M (complement component 3 receptor 3 subunit)
  • domestic guinea pig(100135561) integrin, alpha M (complement component 3 receptor 3 subunit)
  • domestic cat(101087957) integrin, alpha M (complement component 3 receptor 3 subunit)
  • cow(407124) integrin, alpha M (complement component 3 receptor 3 subunit)
  • naked mole-rat(101719288) integrin, alpha M (complement component 3 receptor 3 subunit)
  • Domestic Rabbit(100351865) integrin, alpha M (complement component 3 receptor 3 subunit)

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Antibodies

Product Number
Description
Species Reactivity
Application
ZRB2485
Anti-CD11b Antibody, clone 2K14 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
CBL1512F
Anti-Integrin αM [CD11b] Antibody, clone OX-42, FITC conjugated, clone OX-42, Chemicon®, from mouse,
Species Reactivity
rat
Application
flow cytometry
immunohistochemistry
MABF514
Anti-CD11b Antibody (human/mouse), Biotin, clone M1/70, clone M1/70, 0.5 mg/mL, from rat,
Species Reactivity
human, mouse
Application
flow cytometry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
MABF359
Anti-CD11b Antibody (human/mouse), PerCP-Cy5.5, clone M1/70, clone M1/70, 0.2 mg/mL, from rat,
Species Reactivity
human, mouse
Application
flow cytometry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
MABF517
Anti-CD11b Antibody (human/mouse), PerCP-Cy5.5, clone M1/70, clone M1/70, 0.2 mg/mL, from rat,
Species Reactivity
human, mouse
Application
flow cytometry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)

esiRNA

Product Number
Description
Species
EHU048811
MISSION® esiRNA, targeting human ITGAM,
Species
human
EMU032261
MISSION® esiRNA, targeting mouse Itgam,
Species
mouse