MAP2K5
mitogen-activated protein kinase kinase 5
Synonyms:
HsT17454, MAPKK5, MEK5, PRKMK5
Species:
Human MAP2K5 (5607), Mouse Map2k5 (23938), Rat Map2k5 (29568), Domestic Rabbit MAP2K5 (100358715), domestic cat MAP2K5 (101100725), sheep MAP2K5 (101104069), chicken MAP2K5 (415557), dog MAP2K5 (609559), cow MAP2K5 (100295732), domestic guinea pig Map2k5 (100732076) ...More
UniProtKB ID:
Gene ID:
- Human(5607) Summary: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. [provided by RefSeq, May 2011]
- Mouse(23938) mitogen-activated protein kinase kinase 5
- Rat(29568) mitogen activated protein kinase kinase 5
- Domestic Rabbit(100358715) mitogen-activated protein kinase kinase 5
- domestic cat(101100725) mitogen-activated protein kinase kinase 5
- sheep(101104069) mitogen-activated protein kinase kinase 5
- chicken(415557) mitogen-activated protein kinase kinase 5
- dog(609559) mitogen-activated protein kinase kinase 5
- cow(100295732) mitogen-activated protein kinase kinase 5
- domestic guinea pig(100732076) mitogen-activated protein kinase kinase 5
- naked mole-rat(101711080) mitogen-activated protein kinase kinase 5
- Horse(100052849) mitogen-activated protein kinase kinase 5
- Zebrafish(100007679) mitogen-activated protein kinase kinase 5
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-MEK5 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-MEK5 Antibody, Chemicon®, from rabbit,
Species Reactivity
xenopus, canine, human, monkey, mouse, rabbit, rat, sheep
Application
ELISA
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Small Molecule - Inhibitor
Product Number
Description
Species