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Merck

MAPT

microtubule-associated protein tau

Synonyms:
DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, TAU
Species:
UniProtKB ID:
Gene ID:
  • Human(4137) Summary: This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]
  • Mouse(17762) microtubule-associated protein tau
  • Rat(29477) microtubule-associated protein tau
  • domestic guinea pig(100735442) microtubule-associated protein tau
  • chicken(426737) microtubule-associated protein tau
  • sheep(101121024) microtubule-associated protein tau
  • Domestic Rabbit(100344003) microtubule-associated protein tau
  • cow(281296) microtubule-associated protein tau
  • Goat(100860820) microtubule-associated protein tau
  • domestic cat(101089557) microtubule-associated protein tau
  • Horse(100054638) microtubule-associated protein tau
  • dog(480488) microtubule-associated protein tau
  • naked mole-rat(101719489) microtubule-associated protein tau

Custom & Knockdown Gene Products

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-phospho Tau (Thr181), clone 1E7 Antibody, clone 1E7, from mouse, purified by affinity chromatography,
Species Reactivity
human, mouse
Application
western blot
Anti-Tau Antibody, clone 10C5, ,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry

western blot
Anti-Tau Antibody, clone 9B4, ,
Species Reactivity
human, rhesus macaque
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-Tau Antibody, clone Tau-5 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, human, monkey, mouse, rat, sheep
Application
ELISA
affinity binding assay

immunohistochemistry

western blot
Anti-Tau Antibody, clone Tau 12 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
flow cytometry
immunocytochemistry

immunohistochemistry

western blot

Proteins

Product Number
Description
Species
TAU-316 Protein, recombinant,
Species
human
TAU-441, TTBK1-Phosphorylated, recombinant,
Species
human
SILuProt MAPT Microtubule-associated protein tau-441 human, recombinant, expressed in HEK 293 cells, SIL MS Protein Standard, 13C and 15N-labeled,
Species
human
Tau-410 human, recombinant, expressed in E. coli, ≥85% (SDS-PAGE), lyophilized powder,
Species
human
Tau-383 human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE), lyophilized powder,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MAPT,
Species
human