PDE5A
phosphodiesterase 5A, cGMP-specific
Synonyms:
CGB-PDE, CN5A, PDE5
Species:
Human PDE5A (8654), Mouse Pde5a (242202), Rat Pde5a (171115), naked mole-rat Pde5a (101696421), chicken PDE5A (422677), domestic guinea pig Pde5a (100527958), sheep PDE5A (101109357), sheep PDE5A (100294560), Domestic Rabbit PDE5A (100354625), domestic cat PDE5A (100533976) ...More
UniProtKB ID:
Gene ID:
- Human(8654) Summary: This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
- Mouse(242202) phosphodiesterase 5A, cGMP-specific
- Rat(171115) phosphodiesterase 5A, cGMP-specific
- naked mole-rat(101696421) phosphodiesterase 5A, cGMP-specific
- chicken(422677) phosphodiesterase 5A, cGMP-specific
- domestic guinea pig(100527958) phosphodiesterase 5A, cGMP-specific
- sheep(101109357) phosphodiesterase 5A, cGMP-specific
- sheep(100294560) phosphodiesterase 5A, cGMP-specific
- Domestic Rabbit(100354625) phosphodiesterase 5A, cGMP-specific
- domestic cat(100533976) phosphodiesterase 5A, cGMP-specific
- Horse(100072395) phosphodiesterase 5A, cGMP-specific
- cow(785098) phosphodiesterase 5A, cGMP-specific
- cow(281972) phosphodiesterase 5A, cGMP-specific
- dog(403825) phosphodiesterase 5A, cGMP-specific
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Small Molecule - Inhibitor
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Description
Species
Sildenafil Citrate, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Sildenafil for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
Proteins
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Description
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esiRNA
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Description
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