PPL
periplakin
Synonyms:
Species:
Human PPL (5493), Mouse Ppl (19041), Rat Ppl (302934), fruit fly ppl (40349), Zebrafish ppl (449936), chicken PPL (408044), dog PPL (490021), domestic cat PPL (101091989), Horse PPL (100069951), cow PPL (522886) ...More
UniProtKB ID:
Gene ID:
- Human(5493) Summary: The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling. [provided by RefSeq, Jul 2008]
- Mouse(19041) periplakin
- Rat(302934) periplakin
- fruit fly(40349) pumpless
- Zebrafish(449936) periplakin
- chicken(408044) periplakin
- dog(490021) periplakin
- domestic cat(101091989) periplakin
- Horse(100069951) periplakin
- cow(522886) periplakin
- sheep(101104034) periplakin
- Domestic Rabbit(100343940) periplakin
- domestic guinea pig(100721751) periplakin
- naked mole-rat(101703806) periplakin
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