SH2B2
SH2B adaptor protein 2
Synonyms:
APS
Species:
Human SH2B2 (10603), Mouse Sh2b2 (23921), Rat Sh2b2 (114203), chicken SH2B2 (771172), domestic guinea pig Sh2b2 (100379265), sheep SH2B2 (101117815), cow SH2B2 (617840), dog SH2B2 (489820), naked mole-rat Sh2b2 (101724022), domestic cat SH2B2 (101090410)
UniProtKB ID:
Gene ID:
- Human(10603) Summary: The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway. [provided by RefSeq, Jun 2009]
- Mouse(23921) SH2B adaptor protein 2
- Rat(114203) SH2B adaptor protein 2
- chicken(771172) SH2B adaptor protein 2
- domestic guinea pig(100379265) SH2B adaptor protein 2
- sheep(101117815) SH2B adaptor protein 2
- cow(617840) SH2B adaptor protein 2
- dog(489820) SH2B adaptor protein 2
- naked mole-rat(101724022) SH2B adaptor protein 2
- domestic cat(101090410) SH2B adaptor protein 2
- Horse(100060578) SH2B adaptor protein 2
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