TPP1
tripeptidyl peptidase I
Synonyms:
CLN2, LPIC, TPP-1
Species:
Human TPP1 (1200), Mouse Tpp1 (12751), Rat Tpp1 (83534), domestic cat TPP1 (101093296), dog TPP1 (485337), chicken TPP1 (425576), naked mole-rat Tpp1 (101707185), cow TPP1 (515575), Domestic Rabbit TPP1 (100356773), domestic guinea pig Tpp1 (100733945) ...More
UniProtKB ID:
Gene ID:
- Human(1200) Summary: This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq, Jul 2008]
- Mouse(12751) tripeptidyl peptidase I
- Rat(83534) tripeptidyl peptidase I
- domestic cat(101093296) tripeptidyl peptidase I
- dog(485337) tripeptidyl peptidase I
- chicken(425576) tripeptidyl peptidase I
- naked mole-rat(101707185) tripeptidyl peptidase I
- cow(515575) tripeptidyl peptidase I
- Domestic Rabbit(100356773) tripeptidyl peptidase I
- domestic guinea pig(100733945) tripeptidyl peptidase I
- sheep(101116858) tripeptidyl peptidase I
- Zebrafish(798347) tripeptidyl peptidase I
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-TPP1 Antibody, clone 2E12, clone 2E12, from mouse,
Species Reactivity
human
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot