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Chromatography Systems for Bioprocessing

Single-use and multi-use chromatography systems are critical factors for the successful separation of your valuable molecules. From pilot to process-scale, our systems are designed to provide robust, consistent performance with the processing flexibility you need. We also offer an unmatched portfolio of chromatography resins and membranes, backed by unparalleled applications and validation support. With this complete product offering, we continue to support you in your efforts to increase productivity and process efficiency.

Mobius® Multi Column Capture System

Mobius® Multi Column Capture System (Coming soon)

The Mobius® Multi Column Capture system is a single-use solution for continuous chromatography, utilizing 3 columns, and intuitive and intelligent software, and standardized Flexware® assemblies that allow you to select whether you want to run chromatography in a closed mode. The system can run up to 20 days in continuous mode and allows to increase resin utilization while reducing COGs.

Mobius® Chrom 20 system, for SU processes at clinical and process scale

Mobius® Chrom 20 system

The Mobius® Chrom 20 system is a flexible, fully automated, single-use chromatography system that enables consistent and reliable separation and purification of mAbs, vaccines, plasma, and therapeutic proteins at clinical and commercial scales. The innovative single-use flowpath reduces contamination risk while the flexible design features a standard hardware platform and options, empowering you to meet your unique process requirements. The Mobius® Chrom 20 system delivers optimal operational flexibility for a 2,000 L bioreactor scale, with flow rates from 0.4 L/min (isocratic mode) up to 20 L/min. In gradient mode the system covers flow rates from 4 L/min to 20 L/min, for a 5:1 turn down ratio, with unrivalled isocratic and linear gradient accuracy.

The Mobius® FlexReady Solution with Smart Flexware™ Assemblies is a flexible system, allowing you to have a single, scalable system for chromatography. T

Mobius® FlexReady Solution for chromatography

The Mobius® FlexReady Solution with Smart Flexware® Assemblies is a flexible system, allowing you to have a single, scalable system for chromatography. The fully automated system is designed to achieve separation and purification of mAbs, vaccines, plasma, and therapeutic proteins. The Mobius® FlexReady Solution with Smart Flexware® Assemblies delivers optimal operational flexibility in a very simple and fast way.

CoPrime® System, fully automated system for biopharmaceutical manufacturing and cGMP process scale operations

CoPrime® biochromatography systems

CoPrime® biochromatography systems are designed to achieve optimum separation and purification of monoclonal antibodies, vaccines, plasma, and therapeutic proteins. The systems support rapid scale-up and are ideally suited for pilot and process scale. The CoPrime® systems are based on 50 years of process knowledge and engineering expertise, providing a configurable, intuitive process-scale purification solution. CoPrime® B and C sizes have an extended flow rate span and optimized performance for greater gradient accuracy and purification reproduction. The CoPrime® size C covers higher scales and allows scale-up directly from CoPrime B.


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Highlights

Video: Mobius® Chrom 20 System
For Purification of Biologics at Clinical and Process Scale

Purify your biologics at clinical and process scale, up to 2000 L. Learn how the Mobius® Chrom 20 System can optimize your purification process.

Video
Webinar: Membrane Chromatography Solutions for Single-use, Intensified mAb Purification

The benefits of a novel Protein A affinity membrane, used as a high productivity, truly single-use chromatography platform for intensified mAb purification

Webinar
Webinar: A Novel CEX Resin for the Removal of mAb Aggregate via Flow-through Frontal Chromatography

CEX flow-through frontal chromatography for the removal of mAb aggregates as well as the conditions that influence the removal of these aggregates.

Webinar
Webinar: Custom Affinity Chromatography for Vaccine Purification: A New PD Paradigm

An overview of custom affinity chromatography technologies for vaccine purification.