ACSL5
acyl-CoA synthetase long-chain family member 5
Sinónimos:
ACS2, ACS5, FACL5
Especie:
Human ACSL5 (51703), Mouse Acsl5 (433256), Rat Acsl5 (94340), sheep ACSL5 (101121475), cow ACSL5 (514159), naked mole-rat Acsl5 (101720490), domestic guinea pig Acsl5 (100379229), Horse ACSL5 (100059190), domestic cat ACSL5 (101101342), dog ACSL5 (477820) ...Más
ID UniProtKB:
ID del gen:
- Human(51703) Summary: The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(433256) acyl-CoA synthetase long-chain family member 5
- Rat(94340) acyl-CoA synthetase long-chain family member 5
- sheep(101121475) acyl-CoA synthetase long-chain family member 5
- cow(514159) acyl-CoA synthetase long-chain family member 5
- naked mole-rat(101720490) acyl-CoA synthetase long-chain family member 5
- domestic guinea pig(100379229) acyl-CoA synthetase long-chain family member 5
- Horse(100059190) acyl-CoA synthetase long-chain family member 5
- domestic cat(101101342) acyl-CoA synthetase long-chain family member 5
- dog(477820) acyl-CoA synthetase long-chain family member 5
- chicken(423896) acyl-CoA synthetase long-chain family member 5
- Zebrafish(447860) acyl-CoA synthetase long-chain family member 5
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