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Merck

ATF4

activating transcription factor 4

Sinónimos:
CREB-2, CREB2, TAXREB67, TXREB
Especie:
ID UniProtKB:
ID del gen:
  • Human(468) Summary: This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. [provided by RefSeq, Sep 2011]
  • Mouse(11911) activating transcription factor 4
  • Rat(79255) activating transcription factor 4
  • naked mole-rat(101724287) activating transcription factor 4
  • domestic cat(101084297) activating transcription factor 4 (tax-responsive enhancer element B67)
  • sheep(100216465) activating transcription factor 4 (tax-responsive enhancer element B67)
  • domestic guinea pig(100732296) activating transcription factor 4
  • cow(509107) activating transcription factor 4 (tax-responsive enhancer element B67)
  • dog(474503) activating transcription factor 4 (tax-responsive enhancer element B67)
  • chicken(395693) activating transcription factor 4 (tax-responsive enhancer element B67)

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-ATF4 Antibody, serum, from rabbit,
Reactividad de especies
human
Aplicación
ChIP
western blot
Anti-ATF4 Antibody, clone 1B21 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, canine, feline, human, monkey, mouse, rat
Aplicación
affinity binding assay
immunocytochemistry

western blot

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human ATF4,
Especie
human
MISSION® esiRNA, targeting mouse Atf4,
Especie
mouse