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Merck

CSF1R

colony stimulating factor 1 receptor

Sinónimos:
C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, HDLS, M-CSF-R
Especie:
ID UniProtKB:
ID del gen:
  • Human(1436) Summary: The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. [provided by RefSeq, Jul 2008]
  • Mouse(12978) colony stimulating factor 1 receptor
  • Rat(307403) colony stimulating factor 1 receptor
  • domestic guinea pig(100726053) colony stimulating factor 1 receptor
  • naked mole-rat(101719513) colony stimulating factor 1 receptor
  • sheep(101109969) colony stimulating factor 1 receptor
  • cow(509418) colony stimulating factor 1 receptor
  • domestic cat(493706) colony stimulating factor 1 receptor
  • Horse(100060422) colony stimulating factor 1 receptor
  • dog(489188) colony stimulating factor 1 receptor
  • chicken(396406) colony stimulating factor 1 receptor

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-CSF-1R/CD115 Antibody clone FER216, clone FER216, from mouse,
Reactividad de especies
human
Aplicación
western blot
Monoclonal Anti-CSF1R antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL11653, purified immunoglobulin, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-CSF1R/c-FMS Antibody, clone AFS98, ,
Reactividad de especies
mouse
Aplicación
flow cytometry
Anti-CSF-1R/CD115 Antibody, clone 1F6 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, monkey
Aplicación
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-CD115 (c-fms) Antibody (mouse), PE, clone AFS98, clone AFS98, 0.2 mg/mL, from rat,
Reactividad de especies
mouse
Aplicación
flow cytometry
western blot

Small Molecule - Inhibitor

Número de producto
Descripción
Especie
Sunitinib malate, ≥98% (HPLC),
Especie
human
Pazopanib, ,
Especie
human

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human CSF1R,
Especie
human
MISSION® esiRNA, targeting mouse Csf1r,
Especie
mouse