DCC
deleted in colorectal carcinoma
Sinónimos:
CRC18, CRCR1, IGDCC1, MRMV1
Especie:
Human DCC (1630), Mouse Dcc (13176), Rat Dcc (25311), Zebrafish dcc (569360), dog DCC (483976), domestic cat DCC (101098832), Horse DCC (100054013), cow DCC (537176), sheep DCC (101118654), domestic guinea pig Dcc (100712666)
ID UniProtKB:
ID del gen:
- Human(1630) Summary: This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma. [provided by RefSeq, Oct 2009]
- Mouse(13176) deleted in colorectal carcinoma
- Rat(25311) deleted in colorectal carcinoma
- Zebrafish(569360) deleted in colorectal carcinoma
- dog(483976) deleted in colorectal carcinoma
- domestic cat(101098832) deleted in colorectal carcinoma
- Horse(100054013) deleted in colorectal carcinoma
- cow(537176) deleted in colorectal carcinoma
- sheep(101118654) deleted in colorectal carcinoma
- domestic guinea pig(100712666) deleted in colorectal carcinoma
- naked mole-rat(101705571) deleted in colorectal carcinoma
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
esiRNA
Número de producto
Descripción
Especie