DDR2
discoidin domain receptor tyrosine kinase 2
Sinónimos:
MIG20a, NTRKR3, TKT, TYRO10
Especie:
Human DDR2 (4921), Mouse Ddr2 (18214), Rat Ddr2 (685781), chicken DDR2 (396404), dog DDR2 (478987), Zebrafish ddr2 (559428), domestic guinea pig Ddr2 (100729537), sheep DDR2 (101109754), naked mole-rat Ddr2 (101712349), cow DDR2 (533523) ...Más
ID UniProtKB:
ID del gen:
- Human(4921) Summary: Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
- Mouse(18214) discoidin domain receptor family, member 2
- Rat(685781) discoidin domain receptor tyrosine kinase 2
- chicken(396404) discoidin domain receptor tyrosine kinase 2
- dog(478987) discoidin domain receptor tyrosine kinase 2
- Zebrafish(559428) discoidin domain receptor family, member 2
- domestic guinea pig(100729537) discoidin domain receptor tyrosine kinase 2
- sheep(101109754) discoidin domain receptor tyrosine kinase 2
- naked mole-rat(101712349) discoidin domain receptor tyrosine kinase 2
- cow(533523) discoidin domain receptor tyrosine kinase 2
- Horse(100058300) discoidin domain receptor tyrosine kinase 2
- domestic cat(101085267) discoidin domain receptor tyrosine kinase 2
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Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-DDR2 Antibody, clone 1M8U7, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
western blot
esiRNA
Número de producto
Descripción
Especie