DERL1
derlin 1
Sinónimos:
DER-1, DER1
Especie:
Human DERL1 (79139), Mouse Derl1 (67819), Rat Derl1 (362912), dog DERL1 (475086), domestic cat DERL1 (101100445), Zebrafish derl1 (406753), domestic guinea pig Derl1 (100727484), cow DERL1 (404121), chicken DERL1 (420350), naked mole-rat Derl1 (101722706)
ID UniProtKB:
ID del gen:
- Human(79139) Summary: The protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation. This protein recognizes substrate in the ER and works in a complex to retrotranslocate it across the ER membrane into the cytosol. This protein may select cystic fibrosis transmembrane conductance regulator protein (CFTR) for degradation as well as unfolded proteins in Alzheimer's disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]
- Mouse(67819) Der1-like domain family, member 1
- Rat(362912) derlin 1
- dog(475086) derlin 1
- domestic cat(101100445) derlin 1
- Zebrafish(406753) Der1-like domain family, member 1
- domestic guinea pig(100727484) derlin 1
- cow(404121) derlin 1
- chicken(420350) derlin 1
- naked mole-rat(101722706) derlin 1
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Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-Derlin-1 Antibody, clone 2C2, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, human, mouse, rat
Aplicación
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Derlin-1 Antibody, clone 8G11.2, clone 8G11.2, from mouse,
Reactividad de especies
human, mouse
Aplicación
immunocytochemistry
western blot
western blot