DUSP9
dual specificity phosphatase 9
Sinónimos:
MKP-4, MKP4
Especie:
Human DUSP9 (1852), Mouse Dusp9 (75590), Rat Dusp9 (293847), sheep DUSP9 (101123448), cow DUSP9 (614306), dog DUSP9 (492240), domestic guinea pig Dusp9 (100713707), naked mole-rat Dusp9 (101717115), domestic cat DUSP9 (101080951)
ID UniProtKB:
ID del gen:
- Human(1852) Summary: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases, is expressed only in placenta, kidney, and fetal liver, and is localized to the cytoplasm and nucleus. [provided by RefSeq, Jul 2008]
- Mouse(75590) dual specificity phosphatase 9
- Rat(293847) dual specificity phosphatase 9
- sheep(101123448) dual specificity phosphatase 9
- cow(614306) dual specificity phosphatase 9
- dog(492240) dual specificity phosphatase 9
- domestic guinea pig(100713707) dual specificity phosphatase 9
- naked mole-rat(101717115) dual specificity phosphatase 9
- domestic cat(101080951) dual specificity phosphatase 9
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