FCGR3A
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
Sinónimos:
CD16, CD16A, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, IGFR3
Especie:
Human FCGR3A (2214), Rat Fcgr3a (304966), dog FCGR3A (478984), sheep FCGR3A (100192433), cow FCGR3A (281766)
ID UniProtKB:
ID del gen:
- Human(2214) Summary: This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Rat(304966) Fc fragment of IgG, low affinity IIIa, receptor
- dog(478984) Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
- sheep(100192433) Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
- cow(281766) Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
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Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-CD16a Antibody, clone 1E6 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
Milli-Mark® Anti-CD16-FITC Antibody, clone DJ130c, clone DJ130c, Milli-Mark®, from mouse,
Reactividad de especies
human
Aplicación
flow cytometry
esiRNA
Número de producto
Descripción
Especie