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Merck

FLNA

filamin A, alpha

Sinónimos:
ABP-280, ABPX, CSBS, CVD1, FLN, FLN-A, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD
Especie:
ID UniProtKB:
ID del gen:
  • Human(2316) Summary: The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]
  • Mouse(192176) filamin, alpha
  • Rat(293860) filamin A, alpha
  • domestic guinea pig(100725162) filamin A, alpha
  • Zebrafish(562529) filamin A, alpha (actin binding protein 280)
  • chicken(395261) filamin A, alpha
  • naked mole-rat(101702004) filamin A, alpha
  • Zebrafish(100534866) filamin A, alpha
  • sheep(101120390) filamin A, alpha
  • dog(481084) filamin A, alpha
  • Domestic Rabbit(100328754) filamin A, alpha
  • cow(281165) filamin A, alpha
  • domestic cat(101082637) filamin A, alpha

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-Filamin A Antibody, clone TI10, Ascites Free, clone TI10, 1 mg/mL, from mouse,
Reactividad de especies
bovine, human
Aplicación
flow cytometry
immunocytochemistry

immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Filamin A Antibody, clone TI10, ascites fluid, clone TI10, Chemicon®,
Reactividad de especies
bovine, human
Aplicación
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-Filamin A Antibody, clone PM6/317 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-phospho-Filamin-A (Ser2152) Antibody, clone PS2, clone PS2, from mouse,
Reactividad de especies
human, mouse
Aplicación
immunocytochemistry
immunofluorescence

western blot
[KO Validated]Anti-CD44 antibody produced in mouse, [Knockout Validated]purified monoclonal antibody, buffered aqueous solution,
Reactividad de especies
human, mouse, rat
Aplicación
western blot

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human FLNA,
Especie
human