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Merck

GDNF

glial cell derived neurotrophic factor

Sinónimos:
ATF1, ATF2, HFB1-GDNF, HSCR3
Especie:
ID UniProtKB:
ID del gen:
  • Human(2668) Summary: This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene may be associated with Hirschsprung disease. [provided by RefSeq, Jun 2010]
  • Mouse(14573) glial cell line derived neurotrophic factor
  • Rat(25453) glial cell derived neurotrophic factor
  • chicken(395569) glial cell derived neurotrophic factor
  • sheep(101117619) glial cell derived neurotrophic factor
  • naked mole-rat(101700544) glial cell derived neurotrophic factor
  • domestic cat(101097871) glial cell derived neurotrophic factor
  • dog(489224) glial cell derived neurotrophic factor
  • domestic guinea pig(100717276) glial cell derived neurotrophic factor
  • cow(386587) glial cell derived neurotrophic factor
  • Horse(100067053) glial cell derived neurotrophic factor

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-Glial Derived Neurotrophic Factor Antibody, Chemicon®, from sheep,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
Anti-Glial Derived Neurotrophic Factor Antibody, Chemicon®, from chicken,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
western blot

Proteins

Número de producto
Descripción
Especie
Glial Cell Line-derived Neurotrophic Factor human, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Especie
human
GDNF from mouse, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Especie
mouse
Glial Cell Line-derived Neurotrophic Factor from rat, recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture, ≥97% (SDS-PAGE),
Especie
rat
GDNF human, Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC),
Especie
human
GDNF from rat, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Especie
rat

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human GDNF,
Especie
human