GMDS
GDP-mannose 4,6-dehydratase
Sinónimos:
GMD, SDR3E1
Especie:
Human GMDS (2762), Mouse Gmds (218138), Rat Gmds (291095), domestic cat GMDS (101086651), dog GMDS (488189), Horse GMDS (100057325), Zebrafish gmds (393461), chicken GMDS (420890), sheep GMDS (101101931), cow GMDS (617688)
ID UniProtKB:
ID del gen:
- Human(2762) Summary: GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).[supplied by OMIM, Aug 2009]
- Mouse(218138) GDP-mannose 4, 6-dehydratase
- Rat(291095) GDP-mannose 4, 6-dehydratase
- domestic cat(101086651) GDP-mannose 4,6-dehydratase
- dog(488189) GDP-mannose 4,6-dehydratase
- Horse(100057325) GDP-mannose 4,6-dehydratase
- Zebrafish(393461) GDP-mannose 4,6-dehydratase
- chicken(420890) GDP-mannose 4,6-dehydratase
- sheep(101101931) GDP-mannose 4,6-dehydratase
- cow(617688) GDP-mannose 4,6-dehydratase
- naked mole-rat(101703718) GDP-mannose 4,6-dehydratase
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