HEY2
hairy/enhancer-of-split related with YRPW motif 2
Sinónimos:
CHF1, GRIDLOCK, GRL, HERP1, HESR2, HRT2, bHLHb32
Especie:
Human HEY2 (23493), Mouse Hey2 (15214), Rat Hey2 (155430), cow HEY2 (538619), dog HEY2 (484115), chicken HEY2 (421718), Zebrafish hey2 (58146), naked mole-rat Hey2 (101716129), domestic guinea pig Hey2 (100727826), sheep HEY2 (100271925)
ID UniProtKB:
ID del gen:
- Human(23493) Summary: This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
- Mouse(15214) hairy/enhancer-of-split related with YRPW motif 2
- Rat(155430) hairy/enhancer-of-split related with YRPW motif 2
- cow(538619) hairy/enhancer-of-split related with YRPW motif 2
- dog(484115) hairy/enhancer-of-split related with YRPW motif 2
- chicken(421718) hairy/enhancer-of-split related with YRPW motif 2
- Zebrafish(58146) hairy/enhancer-of-split related with YRPW motif 2
- naked mole-rat(101716129) hairy/enhancer-of-split related with YRPW motif 2
- domestic guinea pig(100727826) hairy/enhancer-of-split related with YRPW motif 2
- sheep(100271925) hairy/enhancer-of-split related with YRPW motif 2
- domestic cat(101083681) hairy/enhancer-of-split related with YRPW motif 2
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