IL12B
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
Sinónimos:
CLMF, CLMF2, IL-12B, NKSF, NKSF2
Especie:
Human IL12B (3593), Mouse Il12b (16160), Rat Il12b (64546), cow IL12B (281857), chicken IL12B (404671), Horse IL12B (100034222), sheep IL12B (443472), naked mole-rat Il12b (101701309), domestic cat IL12B (768273), dog IL12B (403976)
ID UniProtKB:
ID del gen:
- Human(3593) Summary: This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq, Jul 2008]
- Mouse(16160) interleukin 12b
- Rat(64546) interleukin 12B
- cow(281857) interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- chicken(404671) interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- Horse(100034222) interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- sheep(443472) interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- naked mole-rat(101701309) interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- domestic cat(768273) interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- dog(403976) interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- domestic guinea pig(100135554) interleukin 12b
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Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti IL12B Antibody, clone 23GB5970, Rabbit Monoclonal, clone 23GB5970, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reactividad de especies
human, rat
Aplicación
flow cytometry
western blot
western blot
Anti-IL-12B Antibody, clone 1N3 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
ELISA
affinity binding assay
western blot
affinity binding assay
western blot