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Merck

IL7

interleukin 7

Sinónimos:
IL-7
Especie:
ID UniProtKB:
ID del gen:
  • Human(3574) Summary: The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.[provided by RefSeq, Dec 2010]
  • Mouse(16196) interleukin 7
  • Rat(25647) interleukin 7
  • chicken(420193) interleukin 7
  • dog(751768) interleukin 7
  • domestic cat(101084597) interleukin 7
  • cow(280827) interleukin 7
  • sheep(443341) interleukin 7
  • domestic guinea pig(100725811) interleukin 7
  • naked mole-rat(101713773) interleukin 7

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-Interleukin-7/IL-7 Antibody, clone 7B1.1, clone 7B1.1, from mouse,
Reactividad de especies
human
Aplicación
flow cytometry
western blot
Monoclonal Anti-IL7 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL11132, purified antibody (Protein A),
Reactividad de especies
human
Aplicación
immunofluorescence

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human IL7,
Especie
human