KANK1
KN motif and ankyrin repeat domains 1
Sinónimos:
ANKRD15, CPSQ2, KANK
Especie:
Human KANK1 (23189), Mouse Kank1 (107351), Rat Kank1 (309429), sheep KANK1 (101109511), domestic cat KANK1 (101101346), Horse KANK1 (100050757), cow KANK1 (534869), dog KANK1 (100687276), Zebrafish kank1 (777729), chicken KANK1 (395475) ...Más
ID UniProtKB:
ID del gen:
- Human(23189) Summary: The protein encoded by this gene belongs to the Kank family of proteins, which contain multiple ankyrin repeat domains. This family member functions in cytoskeleton formation by regulating actin polymerization. This gene is a candidate tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder. A t(5;9) translocation results in fusion of the platelet-derived growth factor receptor beta gene (PDGFRB) on chromosome 5 with this gene in a myeloproliferative neoplasm featuring severe thrombocythemia. Alternative splicing of this gene results in multiple transcript variants. A related pseuodgene has been identified on chromosome 20. [provided by RefSeq, Mar 2012]
- Mouse(107351) KN motif and ankyrin repeat domains 1
- Rat(309429) KN motif and ankyrin repeat domains 1
- sheep(101109511) KN motif and ankyrin repeat domains 1
- domestic cat(101101346) KN motif and ankyrin repeat domains 1
- Horse(100050757) KN motif and ankyrin repeat domains 1
- cow(534869) KN motif and ankyrin repeat domains 1
- dog(100687276) KN motif and ankyrin repeat domains 1
- Zebrafish(777729) KN motif and ankyrin repeat domains 1
- chicken(395475) KN motif and ankyrin repeat domains 1
- domestic guinea pig(100727320) KN motif and ankyrin repeat domains 1
- naked mole-rat(101702127) KN motif and ankyrin repeat domains 1
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