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Merck

LGI1

leucine-rich, glioma inactivated 1

Sinónimos:
ADLTE, ADPAEF, ADPEAF, EPITEMPIN, EPT, ETL1, IB1099
Especie:
ID UniProtKB:
ID del gen:
  • Human(9211) Summary: This gene is rearranged as a result of translocations in glioblastoma cell lines. The protein contains a hydrophobic segment representing a putative transmembrane domain with the amino terminus located outside the cell. It also contains leucine-rich repeats with conserved cysteine-rich flanking sequences. This gene is predominantly expressed in neural tissues and its expression is reduced in low grade brain tumors and significantly reduced or absent in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. [provided by RefSeq, Jul 2008]
  • Mouse(56839) leucine-rich repeat LGI family, member 1
  • Rat(252892) leucine-rich, glioma inactivated 1
  • sheep(101105294) leucine-rich, glioma inactivated 1
  • dog(477777) leucine-rich, glioma inactivated 1
  • Domestic Rabbit(100344253) leucine-rich, glioma inactivated 1
  • naked mole-rat(101703526) leucine-rich, glioma inactivated 1
  • domestic cat(101088030) leucine-rich, glioma inactivated 1
  • domestic guinea pig(100726518) leucine-rich, glioma inactivated 1
  • cow(617080) leucine-rich, glioma inactivated 1
  • chicken(423802) leucine-rich, glioma inactivated 1

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-LGI1 Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
human, mouse
Aplicación
western blot
Anti-LGI1 Antibody, clone 2P8Z9, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
western blot

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human LGI1,
Especie
human
MISSION® esiRNA, targeting mouse Lgi1,
Especie
mouse