MADD
MAP-kinase activating death domain
Sinónimos:
DENN, IG20, RAB3GEP
Especie:
Human MADD (8567), Mouse Madd (228355), Rat Madd (94193), sheep MADD (101117276), domestic guinea pig Madd (100725450), naked mole-rat Madd (101710698), cow MADD (534306), Horse MADD (100051327), domestic cat MADD (101093297), dog MADD (475982) ...Más
ID UniProtKB:
ID del gen:
- Human(8567) Summary: Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
- Mouse(228355) MAP-kinase activating death domain
- Rat(94193) MAP-kinase activating death domain
- sheep(101117276) MAP-kinase activating death domain
- domestic guinea pig(100725450) MAP-kinase activating death domain
- naked mole-rat(101710698) MAP-kinase activating death domain
- cow(534306) MAP-kinase activating death domain
- Horse(100051327) MAP-kinase activating death domain
- domestic cat(101093297) MAP-kinase activating death domain
- dog(475982) MAP-kinase activating death domain
- chicken(423184) MAP-kinase activating death domain
- Zebrafish(100150917) MAP-kinase activating death domain
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Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
KD-Validated Anti MAP Kinase Activating Death Domain Antibody, clone 24GB110, Rabbit Monoclonal, clone 24GB110, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reactividad de especies
human, rat
Aplicación
flow cytometry
immunofluorescence
western blot
immunofluorescence
western blot