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Merck

MAPK3

mitogen-activated protein kinase 3

Sinónimos:
ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK
Especie:
ID UniProtKB:
ID del gen:
  • Human(5595) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(26417) mitogen-activated protein kinase 3
  • Rat(50689) mitogen activated protein kinase 3
  • Zebrafish(399480) mitogen-activated protein kinase 3
  • domestic cat(101087958) mitogen-activated protein kinase 3
  • cow(531391) mitogen-activated protein kinase 3
  • Horse(100066173) mitogen-activated protein kinase 3
  • dog(479790) mitogen-activated protein kinase 3
  • sheep(101123008) mitogen-activated protein kinase 3
  • naked mole-rat(101702687) mitogen-activated protein kinase 3
  • domestic guinea pig(100725692) mitogen-activated protein kinase 3

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
KD-Validated Anti ERK1 Antibody, clone 23GB2455, Rabbit Monoclonal, clone 23GB2455, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reactividad de especies
human, rat
Aplicación
flow cytometry
western blot
KD-Validated Anti ERK1 Antibody, clone 23GB2450, Rabbit Monoclonal, clone 23GB2450, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reactividad de especies
human
Aplicación
flow cytometry
immunofluorescence

western blot
Anti-phospho-Erk1 (Thr202/Tyr204) + Erk2 (Thr185/Tyr187) Antibody, clone 23GB4520, Rabbit Monoclonal, clone 23GB4520, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reactividad de especies
human
Aplicación
flow cytometry
immunofluorescence

western blot
Milli-Mark Anti-Phospho-Erk1/2 Antibody (Thr202/Tyr204, Thr185/Tyr187)-PE, clone AW39R, Milli-Mark®, from rabbit,
Reactividad de especies
human, mouse, rat
Aplicación
flow cytometry
western blot
Anti-phospho-MAPK 1/2 (Thr203/Ty205) Antibody, clone 14B9.1, clone 14B9.1, from mouse,
Reactividad de especies
human
Aplicación
western blot

Proteins

Número de producto
Descripción
Especie
MAP Kinase 1/Erk1 Protein, active, 10 µg, Active, recombinant, full-length, human MAP Kinase 1/Erk1 containing an N-terminal GST tag, for use in Kinase Assays.,
Especie
human
ERK1, active, GST tagged human, PRECISIO®, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Mapk3,
Especie
mouse
MISSION® esiRNA, targeting human MAPK3,
Especie
human