MCM2
minichromosome maintenance complex component 2
Sinónimos:
BM28, CCNL1, CDCL1, D3S3194, MITOTIN, cdc19
Especie:
Human MCM2 (4171), Mouse Mcm2 (17216), Rat Mcm2 (312538), fruit fly Mcm2 (40973), Thale Cress MCM2 (841056), domestic guinea pig Mcm2 (100722936), naked mole-rat Mcm2 (101710978), sheep MCM2 (101116097), cow MCM2 (510120), domestic cat MCM2 (101090176) ...Más
ID UniProtKB:
ID del gen:
- Human(4171) Summary: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012]
- Mouse(17216) minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
- Rat(312538) minichromosome maintenance complex component 2
- fruit fly(40973) Minichromosome maintenance 2
- Thale Cress(841056) minichromosome maintenance protein 2
- domestic guinea pig(100722936) minichromosome maintenance complex component 2
- naked mole-rat(101710978) minichromosome maintenance complex component 2
- sheep(101116097) minichromosome maintenance complex component 2
- cow(510120) minichromosome maintenance complex component 2
- domestic cat(101090176) minichromosome maintenance complex component 2
- dog(484622) minichromosome maintenance complex component 2
- chicken(416027) minichromosome maintenance complex component 2
- Zebrafish(192338) MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae)
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Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-MCM2 Antibody, clone 0Q10S9, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Phospho-MCM2-S139 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
western blot