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Merck

MTOR

mechanistic target of rapamycin (serine/threonine kinase)

Sinónimos:
FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Especie:
Human MTOR (2475), Mouse Mtor (56717), Rat Mtor (56718), cow MTOR (100139219), Horse MTOR (100051341), Goat MTOR (100860902), dog MTOR (478232), sheep MTOR (100271659), domestic guinea pig Mtor (100724938), chicken MTOR (419455) ...Más
ID UniProtKB:
P42345, Q4LE76, Q5TER1, Q6LE87, Q96QG3, Q9Y4I3
ID del gen:
  • Human(2475) Summary: The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]
  • Mouse(56717) mechanistic target of rapamycin (serine/threonine kinase)
  • Rat(56718) mechanistic target of rapamycin (serine/threonine kinase)
  • cow(100139219) mechanistic target of rapamycin (serine/threonine kinase)
  • Horse(100051341) mechanistic target of rapamycin (serine/threonine kinase)
  • Goat(100860902) mechanistic target of rapamycin (serine/threonine kinase)
  • dog(478232) mechanistic target of rapamycin (serine/threonine kinase)
  • sheep(100271659) mechanistic target of rapamycin (serine/threonine kinase)
  • domestic guinea pig(100724938) mechanistic target of rapamycin (serine/threonine kinase)
  • chicken(419455) mechanistic target of rapamycin (serine/threonine kinase)
  • Domestic Rabbit(100356164) mechanistic target of rapamycin (serine/threonine kinase)
  • fruit fly(36264) Megator
  • Zebrafish(324254) mechanistic target of rapamycin (serine/threonine kinase)
  • naked mole-rat(101725626) mechanistic target of rapamycin (serine/threonine kinase)
  • domestic cat(101098152) mechanistic target of rapamycin (serine/threonine kinase)

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Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
ABS79
Anti-phospho-mTOR (Ser2159) Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
human, mouse, rat, sheep, zebrafish
Aplicación
dot blot
inhibition assay
western blot
15-105
mTOR phosphorylation Pathway Explorer Antibody MiniPack, This Antibody pack of Anti-mTOR antibodies contains Anti-phospho-mTOR Antibody(Ser2481), Anti-phospho-mTOR Antibody (Thr2446), Anti-phospho-mTOR (Ser2448).,
Reactividad de especies
Aplicación
activity assay
09-345
Anti-phospho-mTOR (Thr2446) Antibody, Upstate®, from rabbit,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
SAB5701741
Anti-Phospho-mTOR-S2448 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
05-1564
Anti-mTOR Antibody, clone 21A12.2, clone 21A12.2, from mouse,
Reactividad de especies
human
Aplicación
immunocytochemistry
western blot

Small Molecule - Inhibitor

Número de producto
Descripción
Especie
SML0120
Perhexiline maleate salt, ≥98% (HPLC),
Especie
human

Proteins

Número de producto
Descripción
Especie
14-770-M
mTOR (1362-end) Protein, active, 10 µg, Active, N-terminal FLAG-tagged, recombinant, human mTOR, amino acids 1362-end, for use in Kinase Assays.,
Especie
human

esiRNA

Número de producto
Descripción
Especie
EHU101641
MISSION® esiRNA, targeting human MTOR,
Especie
human