OTX2
orthodenticle homeobox 2
Sinónimos:
CPHD6, MCOPS5
Especie:
Human OTX2 (5015), Mouse Otx2 (18424), Rat Otx2 (305858), domestic guinea pig Otx2 (100729098), domestic cat OTX2 (101094107), naked mole-rat Otx2 (101696878), sheep OTX2 (101114527), chicken OTX2 (395191), cow OTX2 (538953), Domestic Rabbit OTX2 (100009374) ...Más
ID UniProtKB:
ID del gen:
- Human(5015) Summary: This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012]
- Mouse(18424) orthodenticle homolog 2 (Drosophila)
- Rat(305858) orthodenticle homeobox 2
- domestic guinea pig(100729098) orthodenticle homeobox 2
- domestic cat(101094107) orthodenticle homeobox 2
- naked mole-rat(101696878) orthodenticle homeobox 2
- sheep(101114527) orthodenticle homeobox 2
- chicken(395191) orthodenticle homeobox 2
- cow(538953) orthodenticle homeobox 2
- Domestic Rabbit(100009374) orthodenticle homeobox 2
- Zebrafish(30501) orthodenticle homolog 2
- dog(490708) orthodenticle homeobox 2
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Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-OTX2 Antibody, clone 8D8.2, clone 8D8.2, from mouse,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
Anti-OTX2 Antibody, clone 1O4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
xenopus, bovine, horse, human, monkey, porcine, rat
Aplicación
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-OTX2 Antibody, clone 6I3J0, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
western blot