PANK2
pantothenate kinase 2
Sinónimos:
C20orf48, HARP, HSS, NBIA1, PKAN
Especie:
Human PANK2 (80025), Mouse Pank2 (74450), Rat Pank2 (296167), cow PANK2 (535933), naked mole-rat Pank2 (101707167), domestic cat PANK2 (101092510), Zebrafish pank2 (570866), sheep PANK2 (100217410), dog PANK2 (477168), chicken PANK2 (422935) ...Más
ID UniProtKB:
ID del gen:
- Human(80025) Summary: This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
- Mouse(74450) pantothenate kinase 2
- Rat(296167) pantothenate kinase 2
- cow(535933) pantothenate kinase 2
- naked mole-rat(101707167) pantothenate kinase 2
- domestic cat(101092510) pantothenate kinase 2
- Zebrafish(570866) pantothenate kinase 2
- sheep(100217410) pantothenate kinase 2
- dog(477168) pantothenate kinase 2
- chicken(422935) pantothenate kinase 2
- domestic guinea pig(100736048) pantothenate kinase 2
- Thale Cress(829351) pantothenate kinase 2
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Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-PANK2 Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
human
Aplicación
western blot