PARN
poly(A)-specific ribonuclease
Sinónimos:
DAN
Especie:
Human PARN (5073), Mouse Parn (74108), Rat Parn (360464), domestic guinea pig Parn (100732149), naked mole-rat Parn (101715275), cow PARN (524155), Zebrafish parn (791461), Domestic Rabbit PARN (100351489), domestic cat PARN (101100021), dog PARN (479839) ...Más
ID UniProtKB:
ID del gen:
- Human(5073) Summary: The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
- Mouse(74108) poly(A)-specific ribonuclease (deadenylation nuclease)
- Rat(360464) poly(A)-specific ribonuclease
- domestic guinea pig(100732149) poly(A)-specific ribonuclease
- naked mole-rat(101715275) poly(A)-specific ribonuclease
- cow(524155) poly(A)-specific ribonuclease
- Zebrafish(791461) poly(A)-specific ribonuclease (deadenylation nuclease)
- Domestic Rabbit(100351489) poly(A)-specific ribonuclease
- domestic cat(101100021) poly(A)-specific ribonuclease
- dog(479839) poly(A)-specific ribonuclease
- chicken(416423) poly(A)-specific ribonuclease
- sheep(101112185) poly(A)-specific ribonuclease
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