PDCD10
programmed cell death 10
Sinónimos:
CCM3, TFAR15
Especie:
Human PDCD10 (11235), Mouse Pdcd10 (56426), Rat Pdcd10 (494345), sheep PDCD10 (101122826), dog PDCD10 (488145), naked mole-rat Pdcd10 (101715475), cow PDCD10 (506411), chicken PDCD10 (425003), domestic cat PDCD10 (101090640), domestic guinea pig Pdcd10 (100729780)
ID UniProtKB:
ID del gen:
- Human(11235) Summary: This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
- Mouse(56426) programmed cell death 10
- Rat(494345) programmed cell death 10
- sheep(101122826) programmed cell death 10
- dog(488145) programmed cell death 10
- naked mole-rat(101715475) programmed cell death 10
- cow(506411) programmed cell death 10
- chicken(425003) programmed cell death 10
- domestic cat(101090640) programmed cell death 10
- domestic guinea pig(100729780) programmed cell death 10
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