Saltar al contenido
Merck

PDE1B

phosphodiesterase 1B, calmodulin-dependent

Sinónimos:
PDE1B1, PDES1B
Especie:
ID UniProtKB:
ID del gen:
  • Human(5153) Summary: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
  • Mouse(18574) phosphodiesterase 1B, Ca2+-calmodulin dependent
  • Rat(29691) phosphodiesterase 1B, calmodulin-dependent
  • domestic guinea pig(100527959) phosphodiesterase 1B, Ca2+-calmodulin dependent
  • naked mole-rat(101718122) phosphodiesterase 1B, calmodulin-dependent
  • sheep(101118773) phosphodiesterase 1B, calmodulin-dependent
  • Domestic Rabbit(100341084) phosphodiesterase 1B, calmodulin-dependent
  • Horse(100064711) phosphodiesterase 1B, calmodulin-dependent
  • cow(281970) phosphodiesterase 1B, calmodulin-dependent
  • dog(100856025) phosphodiesterase 1B, calmodulin-dependent
  • domestic cat(101094608) phosphodiesterase 1B, calmodulin-dependent

Custom & Knockdown Gene Products

Small Molecule - Inhibitor

Número de producto
Descripción
Especie
8-Methoxymethyl-3-isobutyl-1-methylxanthine, ≥98%,
Especie
human
Vinpocetine, ≥98%, solid,
Especie
human
Theophylline, anhydrous, ≥99%, powder,
Especie
mouse, human, rat
Dipyridamole, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Dipyridamole for peak identification, European Pharmacopoeia (EP) Reference Standard,
Especie
human

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human PDE1B,
Especie
human
MISSION® esiRNA, targeting mouse Pde1b,
Especie
mouse