RNF170
ring finger protein 170
Sinónimos:
SNAX1
Especie:
Human RNF170 (81790), Mouse Rnf170 (77733), Rat Rnf170 (364654), chicken RNF170 (427296), Zebrafish rnf170 (406612), naked mole-rat Rnf170 (101705067), domestic guinea pig Rnf170 (100719157), sheep RNF170 (101120050), cow RNF170 (617379), domestic cat RNF170 (101097313)
ID UniProtKB:
ID del gen:
- Human(81790) Summary: This gene encodes a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1,4,5-trisphosphate (IP3) receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1/ERLIN2 complex to which it is constitutively bound. Mutations in this gene are associated with autosomal dominant sensory ataxia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]
- Mouse(77733) ring finger protein 170
- Rat(364654) ring finger protein 170
- chicken(427296) ring finger protein 170
- Zebrafish(406612) ring finger protein 170
- naked mole-rat(101705067) ring finger protein 170
- domestic guinea pig(100719157) ring finger protein 170
- sheep(101120050) ring finger protein 170
- cow(617379) ring finger protein 170
- domestic cat(101097313) ring finger protein 170
- dog(475568) ring finger protein 170
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