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Merck

RUNX2

runt-related transcription factor 2

Sinónimos:
AML3, CBF-alpha-1, CBFA1, CCD, CCD1, CLCD, OSF-2, OSF2, PEA2aA, PEBP2aA
Especie:
ID UniProtKB:
ID del gen:
  • Human(860) Summary: This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2008]
  • Mouse(12393) runt related transcription factor 2
  • Rat(367218) runt-related transcription factor 2
  • Goat(100861217) runt-related transcription factor 2
  • domestic guinea pig(100734175) runt-related transcription factor 2
  • cow(536911) runt-related transcription factor 2
  • chicken(373919) runt-related transcription factor 2
  • Domestic Rabbit(100008943) runt-related transcription factor 2
  • Horse(100033890) runt-related transcription factor 2
  • domestic cat(101089612) runt-related transcription factor 2
  • sheep(101115489) runt-related transcription factor 2
  • dog(474923) runt-related transcription factor 2
  • dog(449531) runt-related transcription factor 2
  • naked mole-rat(101724767) runt-related transcription factor 2

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
ANTI-RUNX2 antibody produced in mouse, clone 4E5, ascites fluid,
Reactividad de especies
human
Aplicación
ELISA
western blot
ANTI-RUNX2 antibody produced in mouse, clone 4B4, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
western blot
Anti-RUNX2 Antibody, clone AS110, clone AS110, from mouse,
Reactividad de especies
human
Aplicación
immunocytochemistry
western blot
Anti-RUNX2 Antibody, clone 7O7J4, Rabbit Monoclonal, ,
Reactividad de especies
mouse
Aplicación
immunoprecipitation (IP)
western blot

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human RUNX2,
Especie
human