SCARB2
scavenger receptor class B, member 2
Sinónimos:
AMRF, CD36L2, EPM4, HLGP85, LGP85, LIMP-2, LIMPII, SR-BII
Especie:
Human SCARB2 (950), Mouse Scarb2 (12492), Rat Scarb2 (117106), dog SCARB2 (478435), Domestic Rabbit SCARB2 (100352345), sheep SCARB2 (101105502), cow SCARB2 (533177), naked mole-rat Scarb2 (101715798), domestic guinea pig Scarb2 (100716020), chicken SCARB2 (422638) ...Más
ID UniProtKB:
ID del gen:
- Human(950) Summary: The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
- Mouse(12492) scavenger receptor class B, member 2
- Rat(117106) scavenger receptor class B, member 2
- dog(478435) scavenger receptor class B, member 2
- Domestic Rabbit(100352345) scavenger receptor class B, member 2
- sheep(101105502) scavenger receptor class B, member 2
- cow(533177) scavenger receptor class B, member 2
- naked mole-rat(101715798) scavenger receptor class B, member 2
- domestic guinea pig(100716020) scavenger receptor class B, member 2
- chicken(422638) scavenger receptor class B, member 2
- Zebrafish(192340) scavenger receptor class B, member 2
- domestic cat(101098789) scavenger receptor class B, member 2
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Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-SR-B2/LIMPII antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
Anti-LIMP II Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
KD-Validated Anti SCARB2 Antibody, clone 24GB1520, Rabbit Monoclonal, clone 24GB1520, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reactividad de especies
human, rat
Aplicación
flow cytometry
western blot
western blot