SETMAR
SET domain and mariner transposase fusion gene
Sinónimos:
HsMar1, METNASE, Mar1
Especie:
Human SETMAR (6419), Mouse Setmar (74729), Rat Setmar (500281), naked mole-rat Setmar (101704237), domestic cat SETMAR (101088560), cow SETMAR (511299), Zebrafish setmar (564575), dog SETMAR (476549), sheep SETMAR (101110273)
ID UniProtKB:
ID del gen:
- Human(6419) Summary: This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
- Mouse(74729) SET domain without mariner transposase fusion
- Rat(500281) SET domain without mariner transposase fusion
- naked mole-rat(101704237) SET domain and mariner transposase fusion gene
- domestic cat(101088560) SET domain without mariner transposase fusion
- cow(511299) SET domain without mariner transposase fusion
- Zebrafish(564575) SET domain without mariner transposase fusion
- dog(476549) SET domain without mariner transposase fusion
- sheep(101110273) SET domain gene
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